Description

2-(5-Aminopyridin-2-Yl)-2-Methylpropanenitrile is a high-value, functionalized pyridine derivative featuring both an aminopyridine moiety and a nitrile group. This unique bifunctional structure makes it a critical pharmaceutical intermediate and a versatile building block for advanced organic synthesis. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the creation of novel active compounds and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Serves as a building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal catalysis and organocatalysts due to its coordinating amine and nitrile functionalities.
• Material Science Research: Employed in the synthesis of functional polymers, dyes, and advanced organic materials.
• Chemical Biology Probes: Utilized as a scaffold for creating molecular probes and diagnostic agents in biochemical research.

Basic Information

Product Name	2-(5-Aminopyridin-2-Yl)-2-Methylpropanenitrile
CAS No.	1226776-95-9
Molecular Formula	C9H11N3
Molecular Weight	161.21 g/mol
Synonyms	2-(5-Amino-2-pyridinyl)-2-methylpropanenitrile; 2-Methyl-2-(5-aminopyridin-2-yl)propanenitrile; 2-(5-Aminopyridin-2-yl)-2-methylpropionitrile; 2-(5-Amino-2-pyridyl)-2-methylpropionitrile; 2-(5-Aminopyridin-2-yl)isobutyronitrile; 5-Amino-2-(2-cyano-2-propyl)pyridine; 2-(5-Amino-2-pyridyl)-2-methylpropanenitrile
EINECS	Contact for details

Quality Control

Our 2-(5-Aminopyridin-2-Yl)-2-Methylpropanenitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent quality suitable for research and commercial-scale synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.