Description

5-(Thiophen-2-Yl)Pyridin-3-Amine is a high-purity heterocyclic aromatic amine building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceuticals and functional materials, enabling the creation of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing active pharmaceutical ingredients (APIs), ligands, and organic electronic components.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Development: Used in creating advanced active ingredients for crop protection products, leveraging its heterocyclic structure for bioactivity.
• Material Science Precursor: Serves as a monomer or functional unit in the synthesis of organic semiconductors, conductive polymers, and light-emitting materials for OLED applications.
• Ligand Synthesis: Employed in the preparation of complex chelating ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research: A versatile scaffold in medicinal and combinatorial chemistry for structure-activity relationship (SAR) studies and library generation.
• Dye and Pigment Intermediate: Used in the synthesis of specialized dyes and pigments due to its fused thiophene-pyridine core.

Basic Information

Product Name	5-(Thiophen-2-Yl)Pyridin-3-Amine
CAS No.	1226415-45-7
Molecular Formula	C9H8N2S
Molecular Weight	176.24 g/mol
Synonyms	3-Amino-5-(2-thienyl)pyridine; 5-(2-Thienyl)-3-pyridinamine; 5-(Thiophen-2-yl)pyridin-3-amine; 3-Pyridinamine, 5-(2-thienyl)-; 5-(2-Thienyl)-3-aminopyridine; 5-(Thiophen-2-Yl)-3-Pyridinamine; 5-(2-Thienyl)nicotinamine
EINECS	Contact for details

Quality Control

Our 5-(Thiophen-2-Yl)Pyridin-3-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.