Description

1-(2-Chloro-6-Fluorophenyl)Propan-1-Ol is a high-purity fluorinated chiral alcohol intermediate of significant importance in advanced organic synthesis. Its value lies in its unique molecular structure, which serves as a critical building block for the development of complex, bioactive molecules. This compound is essential for research and production in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Material Science Research: Employed in the development of specialty chemicals and advanced polymers with specific optical or electronic properties.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	1-(2-Chloro-6-Fluorophenyl)Propan-1-Ol
CAS No.	1226405-69-1
Molecular Formula	C9H10ClFO
Molecular Weight	188.63 g/mol
Synonyms	1-(2-Chloro-6-fluorophenyl)-1-propanol; 1-Propanol, 1-(2-chloro-6-fluorophenyl)-; 2-Chloro-6-fluoro-α-ethylbenzyl alcohol; α-Ethyl-2-chloro-6-fluorobenzyl alcohol; (2-Chloro-6-fluorophenyl)(ethyl)methanol; 1226405-69-1; 1-(2-Chloro-6-fluorophenyl)propan-1-ol
EINECS	Contact for details

Quality Control

Our 1-(2-Chloro-6-Fluorophenyl)Propan-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to ensure enantiomeric excess, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.