Description

6-(3,5-Difluorophenyl)Picolinic Acid is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its unique molecular architecture, which combines a picolinic acid moiety with a difluorophenyl group, making it a critical intermediate for constructing complex molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the difluorophenyl motif.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Advanced Material Development: A monomer or additive in the research of specialty polymers and functional materials.

Basic Information

Product Name	6-(3,5-Difluorophenyl)Picolinic Acid
CAS No.	1226098-50-5
Molecular Formula	C12H7F2NO2
Molecular Weight	235.19 g/mol
Synonyms	2-Pyridinecarboxylic acid, 6-(3,5-difluorophenyl)-; 6-(3,5-Difluorophenyl)-2-pyridinecarboxylic acid; 6-(3,5-Difluorophenyl)picolinate; 2-Carboxy-6-(3,5-difluorophenyl)pyridine; 3,5-Difluoro-6'-picolinic acid (phenyl derivative)
EINECS	Contact for details

Quality Control

Our 6-(3,5-Difluorophenyl)Picolinic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.