Description

5-(3,5-Difluorophenyl)Pyridin-3-Amine is a high-purity, advanced pharmaceutical intermediate featuring a unique difluorophenyl-pyridine scaffold. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and advanced material sectors for developing next-generation therapeutics and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of kinase inhibitors and other small-molecule drug candidates.
• Agrochemical Research: Used in the synthesis of novel herbicides and fungicides, leveraging the biological activity of the difluorophenyl moiety.
• Material Science: Serves as a precursor for functionalized ligands and organic electronic materials.
• Chemical Synthesis: Employed in cross-coupling reactions and as a versatile amine-containing building block for constructing complex heterocyclic systems.
• Bioconjugation: The amine group allows for conjugation to biomolecules or solid supports for diagnostic or research applications.

Basic Information

Product Name	5-(3,5-Difluorophenyl)Pyridin-3-Amine
CAS No.	1225914-83-9
Molecular Formula	C11H8F2N2
Molecular Weight	206.19 g/mol
Synonyms	3-Amino-5-(3,5-difluorophenyl)pyridine; 5-(3,5-Difluorophenyl)-3-pyridinamine; 3-Pyridinamine, 5-(3,5-difluorophenyl)-; 5-(3,5-Difluorophenyl)pyridin-3-ylamine; 1225914-83-9; 5-(3,5-Difluorophenyl)-3-aminopyridine
EINECS	Contact for details

Quality Control

Our 5-(3,5-Difluorophenyl)Pyridin-3-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports applications requiring GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.