Description

3-(Pyridin-2-Yloxy)-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a unique heterocyclic scaffold. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing novel bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of potential drug candidates and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and metabolic disorders.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides, fungicides, or insecticides with specific modes of action.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Ligand Development: Useful for creating novel ligands for catalysis or receptor binding studies due to its pyridine and pyrrolidine motifs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific molecular framework.

Basic Information

Product Name	3-(Pyridin-2-Yloxy)-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1224514-70-8
Molecular Formula	C14H20N2O3
Molecular Weight	264.32 g/mol
Synonyms	1-Boc-3-(2-pyridyloxy)pyrrolidine; tert-Butyl 3-(pyridin-2-yloxy)pyrrolidine-1-carboxylate; 3-(2-Pyridyloxy)-1-(tert-butoxycarbonyl)pyrrolidine; 1-(tert-Butoxycarbonyl)-3-(2-pyridinyloxy)pyrrolidine; Pyrrolidine-1-carboxylic acid, 3-(2-pyridinyloxy)-, 1,1-dimethylethyl ester; 3-(Pyridin-2-yloxy)pyrrolidine-1-carboxylic acid tert-butyl ester; Boc-3-(2-Pyridyloxy)pyrrolidine
EINECS	Contact for details

Quality Control

Our 3-(Pyridin-2-Yloxy)-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high standards, such as pharmaceutical R&D and GMP (Good Manufacturing Practice) starting material preparation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive (store away from light). Keep the container tightly sealed to prevent moisture absorption and contamination. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.