Description

Methyl 6-Chloro-4-Methylnicotinate is a high-purity, versatile nicotinate ester derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized pyridine core, enabling efficient downstream modifications for creating complex molecular architectures. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

This specialized chemical intermediate enables key synthetic pathways across several high-value industries:

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridine structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and material science.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development and exploring new chemical entities.
• Fine Chemical Production: Integral to the custom synthesis of complex, high-value specialty chemicals for various technological applications.

Basic Information

Product Name	Methyl 6-Chloro-4-Methylnicotinate
CAS No.	1224464-97-4
Molecular Formula	C8H8ClNO2
Molecular Weight	185.61 g/mol
Synonyms	6-Chloro-4-methylnicotinic acid methyl ester; Methyl 6-chloro-4-methylpyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 6-chloro-4-methyl-, methyl ester; 6-Chloro-4-methyl-3-pyridinecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 6-Chloro-4-Methylnicotinate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to cGMP principles and rigorous in-process controls guarantees a reliable supply of this high-value intermediate for your most demanding synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.