Description

Redaporfin is a synthetic bacteriochlorin derivative developed as a potent photosensitizer for photodynamic therapy (PDT). This compound matters for its high selectivity and efficacy in generating cytotoxic singlet oxygen upon light activation, offering a targeted approach for treating oncological and microbiological conditions. It is primarily needed by pharmaceutical R&D teams, clinical research organizations, and manufacturers developing next-generation photodynamic therapeutics for cancer and antimicrobial applications. Redaporfin CAS NO 1224104-08-8 represents a key advanced intermediate in the creation of innovative, light-activated medical treatments.

Application

• Photodynamic Therapy (PDT) for Oncology: As a core photosensitizer in clinical and preclinical research for treating various solid tumors.
• Antimicrobial Photodynamic Therapy (aPDT): For research into light-activated treatments targeting antibiotic-resistant bacteria and other pathogens.
• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of advanced, targeted PDT drug candidates.
• Bioconjugation Studies: Used in R&D for attaching targeting moieties like antibodies or peptides to enhance cellular specificity.
• Mechanism of Action Research: Employed in academic and industrial labs to study singlet oxygen generation, cellular uptake, and apoptosis pathways.
• Formulation Development: For creating stable, injectable, or topical formulations suitable for clinical administration.

Basic Information

Product Name	Redaporfin
CAS No.	1224104-08-8
Molecular Formula	C46H54N6O6
Molecular Weight	786.96 g/mol
Synonyms	LUZ11; Bacteriochlorin LUZ11; 5,10,15,20-Tetrakis(3-hydroxyphenyl)bacteriochlorin; 5,10,15,20-Tetrakis(3-hydroxyphenyl)-2,3-dihydro-21H,23H-porphine; Redaporfin (USAN); Tetrahydroxyphenyl Bacteriochlorin; Photosensitizer LUZ11; PDT Agent LUZ11
EINECS	Contact for details

Quality Control

Our Redaporfin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development purposes. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. While not currently compendial (USP/EP), our quality protocols are designed to meet the exacting standards required for pharmaceutical R&D and preclinical studies.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties of being strictly light-sensitive and easily oxidized, this material must be stored under an inert atmosphere (e.g., argon or nitrogen) in a freezer at -20°C or below. Allow the sealed container to reach room temperature before opening to prevent moisture condensation. The storage area should be cool, dry, and well-ventilated.

Specification

Item	Specification
Appearance	Dark green to black solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Single Largest Unknown Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.