Description

5-Bromo-6-Iodopyridin-2-Amine is a high-purity, halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its dual halogen functionality, which enables selective cross-coupling reactions and facilitates the construction of complex heterocyclic scaffolds. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its reactive halogen sites.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and organic electronic materials.
• Cross-Coupling Reactions: An essential substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions due to its bromo and iodo substituents.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Ligand Synthesis: Acts as a starting material for the preparation of complex chelating ligands used in catalysis and metal coordination chemistry.

Basic Information

Product Name	5-Bromo-6-Iodopyridin-2-Amine
CAS No.	1223748-35-3
Molecular Formula	C5H4BrIN2
Molecular Weight	298.91 g/mol
Synonyms	2-Amino-5-bromo-6-iodopyridine; 5-Bromo-6-iodopyridin-2-ylamine; 6-Iodo-5-bromopyridin-2-amine; 2-Pyridinamine, 5-bromo-6-iodo-; (5-Bromo-6-iodopyridin-2-yl)amine; 5-Bromo-6-iodo-2-aminopyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-Iodopyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and reliability for your critical synthetic workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.