Description

1-(5-Methyl-3-(2-Pyridylamino)-2,4-Thiazolyl)Ethan-1-One, Hydrochloride is a high-purity, specialized organic compound with the CAS number 1223343-03-0. This molecule is valued for its unique heterocyclic structure, which serves as a critical building block in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector. The compound's specific reactivity profile makes it an essential intermediate for synthesizing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used as a core scaffold for developing new pesticides and herbicides with targeted modes of action.
• Chemical Biology Probe: Serves as a tool compound for studying enzyme inhibition and protein-ligand interactions in biochemical assays.
• Material Science: Potential monomer or additive for creating specialized polymers with unique electronic or photophysical properties.
• Academic & Institutional Research: Employed in universities and research institutes for methodological development and discovery chemistry projects.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production of client-specific molecules.

Basic Information

Item	Details
Product Name	1-(5-Methyl-3-(2-Pyridylamino)-2,4-Thiazolyl)Ethan-1-One, Hydrochloride
CAS No.	1223343-03-0
Molecular Formula	C11H12N3OS • HCl
Molecular Weight	269.75 g/mol (Free base: 234.30 g/mol)
Synonyms	1-(5-Methyl-3-((pyridin-2-yl)amino)-1,3-thiazol-2(3H)-ylidene)ethan-1-one hydrochloride; 2-Acetyl-5-methyl-3-(2-pyridylamino)thiazole hydrochloride; 3-(2-Pyridinylamino)-5-methyl-2-thiazolyl methyl ketone hydrochloride; 1-[5-Methyl-3-(pyridin-2-ylamino)-1,3-thiazol-2-ylidene]ethanone hydrochloride; 2-Acetyl-3-(2-aminopyridin-3-yl)-5-methylthiazole hydrochloride (tautomeric form); AKOS BRN 0972; ZINC000003869756
EINECS	Contact for details

Quality Control

Every batch of 1-(5-Methyl-3-(2-Pyridylamino)-2,4-Thiazolyl)Ethan-1-One, Hydrochloride is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We support development from research to commercial scale with consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.