Description

9-(6-Amino-3-Pyridinyl)-1-[3-(Trifluoromethyl)Phenyl]Benzo[H]-1,6-Naphthyridin-2(1H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry research and development, particularly for its potential role in modulating specific biological targets. It is primarily sought after by R&D teams and process chemists in the pharmaceutical and biotechnology sectors for the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop compounds with improved efficacy and pharmacokinetic profiles.
• Kinase Inhibitor Development: Serves as a core scaffold or precursor in the development of potent and selective kinase inhibitors due to its naphthyridine-based structure.
• Biochemical Probe Synthesis: Employed to create tool compounds for investigating biological pathways and validating novel drug targets in preclinical research.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex molecules for clinical trials.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and chemical biology.

Basic Information

Product Name	9-(6-Amino-3-Pyridinyl)-1-[3-(Trifluoromethyl)Phenyl]Benzo[H]-1,6-Naphthyridin-2(1H)-One
CAS No.	1223001-51-1
Molecular Formula	C24H15F3N4O
Molecular Weight	432.40 g/mol
Synonyms	9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]-1,6-naphthyridin-2(1H)-one; Benzo[h]-1,6-naphthyridin-2(1H)-one, 9-(6-amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]-; 1223001-51-1; 9-(6-Aminopyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one; 1,6-Naphthyridine derivative CAS 1223001-51-1
EINECS	Contact for details

Quality Control

Our 9-(6-Amino-3-Pyridinyl)-1-[3-(Trifluoromethyl)Phenyl]Benzo[H]-1,6-Naphthyridin-2(1H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.