Description

8-Bromoimidazo[1,2-A]Pyridine-6-Carbonitrile CAS NO 1221791-93-0 is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which incorporates bromine and nitrile functional groups on an imidazopyridine scaffold, enabling precise derivatization for creating complex molecular libraries. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides, leveraging its halogenated heterocyclic structure.
• Material Science: Acts as a building block for constructing organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology Probe Synthesis: Utilized to create tagged or functionalized molecules for studying biological pathways and protein interactions.
• Academic & Contract Research: Employed in university and CRO settings for methodological development and exploring new chemical spaces in heterocyclic chemistry.
• Scale-up & Process Chemistry: Provides a defined starting point for optimizing synthetic routes and developing cost-effective, scalable manufacturing processes for target molecules.

Basic Information

Product Name	8-Bromoimidazo[1,2-A]Pyridine-6-Carbonitrile
CAS No.	1221791-93-0
Molecular Formula	C8H4BrN3
Molecular Weight	222.04 g/mol
Synonyms	8-Bromo-6-cyanoimidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine-6-carbonitrile, 8-bromo-; 8-Bromoimidazo[1,2-a]pyridine-6-carbonitrile; 1221791-93-0; 8-Bromo-6-imidazo[1,2-a]pyridinecarbonitrile; 6-Cyano-8-bromoimidazo[1,2-a]pyridine
EINECS	Contact for details

Quality Control

Our 8-Bromoimidazo[1,2-A]Pyridine-6-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements of research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/MS)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.