Description

2,3,5-Trichloroisonicotinonitrile is a halogenated pyridine derivative that serves as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its unique substitution pattern makes it a critical building block for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce a functionalized, chlorinated pyridine core into their target structures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the trichloropyridine moiety contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or molecular semiconductors.
• Custom Synthesis and Contract Manufacturing: A valuable scaffold for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2,3,5-Trichloroisonicotinonitrile
CAS No.	1221791-83-8
Molecular Formula	C6HCl3N2
Molecular Weight	207.44 g/mol
Synonyms	2,3,5-Trichloro-4-cyanopyridine; 4-Cyano-2,3,5-trichloropyridine; 2,3,5-Trichloropyridine-4-carbonitrile; 2,3,5-Trichloro-4-pyridinecarbonitrile; Isonicotinonitrile, 2,3,5-trichloro-; Trichloroisonicotinonitrile
EINECS	Contact for details

Quality Control

Every batch of 2,3,5-Trichloroisonicotinonitrile is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. Our products undergo rigorous quality testing, including HPLC, GC, NMR, and MS analysis, to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.