Description

1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylic Acid, 3-Bromo-, Methyl Ester is a high-purity, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, agrochemical research, and material science.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new pharmacophores.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new pesticides and herbicides with specific modes of action.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and enzyme functions.
• Material Science: A potential monomer or precursor for creating specialized polymers and organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylic Acid, 3-Bromo-, Methyl Ester
CAS No.	1221288-27-2
Molecular Formula	C9H6BrN3O2
Molecular Weight	268.07 g/mol
Synonyms	3-Bromo-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid methyl ester; Methyl 3-bromo-1H-pyrazolo[3,4-b]pyridine-5-carboxylate; 3-Bromo-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid methyl ester; 1H-Pyrazolo[3,4-b]pyridine-5-carboxylic acid, 3-bromo-, methyl ester; 1221288-27-2; 3-Bromo-1H-pyrazolo[3,4-b]pyridine-5-methyl carboxylate
EINECS	Contact for details

Quality Control

Our 1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylic Acid, 3-Bromo-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.