Description

3-Iodo-1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylic Acid is a high-value, halogenated heterocyclic building block essential for advanced organic synthesis. This compound matters as a key intermediate in the development of novel pharmaceutical agents, particularly in kinase inhibitor research and other targeted therapies. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various disease pathways.
• Agrochemical Research: Used in the discovery and development of new active ingredients for crop protection products.
• Chemical Biology Probe Synthesis: Serves as a versatile scaffold for creating molecular probes to study protein function and biological mechanisms.
• Material Science: Potential building block for advanced organic electronic materials and metal-organic frameworks (MOFs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process scale-up for client projects.
• Academic Research: Utilized in university and institutional labs for methodological development and exploratory chemistry.

Basic Information

Product Name	3-Iodo-1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylic Acid
CAS No.	1221288-26-1
Molecular Formula	C7H4IN3O2
Molecular Weight	288.03 g/mol
Synonyms	3-Iodo-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid; 5-Carboxy-3-iodo-1H-pyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridine-5-carboxylic acid, 3-iodo-; 3-Iodo-1H-pyrazolo[3,4-b]pyridine-5-carboxylate; 1221288-26-1; 3-Iodo-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid (CAS 1221288-26-1)
EINECS	Contact for details

Quality Control

Our 3-Iodo-1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.