Description

6-Chloro-3-Iodo-2-(Trifluoromethoxy)Pyridine is a high-value, multi-functional halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring chlorine, iodine, and a trifluoromethoxy group, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the halogen and trifluoromethoxy groups enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for sophisticated ligands in transition metal catalysis, enabling challenging cross-coupling and functionalization reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or emissive materials for OLEDs, due to its electron-deficient aromatic core.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	6-Chloro-3-Iodo-2-(Trifluoromethoxy)Pyridine
CAS No.	1221171-95-4
Molecular Formula	C6H2ClF3INO
Molecular Weight	337.44 g/mol
Synonyms	2-(Trifluoromethoxy)-6-chloro-3-iodopyridine; 3-Iodo-6-chloro-2-(trifluoromethoxy)pyridine; 6-Chloro-3-iodo-2-(trifluoromethoxy)pyridine; Pyridine, 6-chloro-3-iodo-2-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Every batch of 6-Chloro-3-Iodo-2-(Trifluoromethoxy)Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and GC-MS, is supplied with each shipment to guarantee identity, purity, and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to minimize exposure to moisture. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.