Description

2-Pyridinecarboxylic Acid, 6-Chloro-5-(Trifluoromethoxy)- is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring a pyridine core substituted with chloro, trifluoromethoxy, and carboxylic acid groups, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, where its specific substitution pattern can impart crucial bioactivity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in areas requiring halogenated and fluorinated heterocycles for enhanced potency and pharmacokinetic profiles.
• Agrochemical Synthesis: Serves as a vital precursor in the creation of advanced herbicides, insecticides, and fungicides, leveraging the trifluoromethoxy group for improved lipophilicity and biological activity.
• Material Science Research: Used in the development of specialty chemicals, ligands for catalysis, and advanced organic materials where its specific electronic properties are beneficial.
• Chemical Biology & Proteomics: Employed as a building block for designing molecular probes, enzyme inhibitors, and other tools for biochemical research.

Basic Information

Product Name	2-Pyridinecarboxylic Acid, 6-Chloro-5-(Trifluoromethoxy)-
CAS No.	1221171-90-9
Molecular Formula	C8H3ClF3NO3
Molecular Weight	253.56 g/mol
Synonyms	6-Chloro-5-(trifluoromethoxy)picolinic acid; 6-Chloro-5-(trifluoromethoxy)pyridine-2-carboxylic acid; 2-Pyridinecarboxylic acid, 6-chloro-5-(trifluoromethoxy)-; 6-Chloro-5-trifluoromethoxypicolinic acid; 6-Chloro-5-(trifluoromethoxy)-2-pyridinecarboxylic acid; 6-Chloro-5-(trifluoromethoxy)-2-picolinic acid; 6-Chloro-5-(trifluoromethoxy)picolinate
EINECS	Contact for details

Quality Control

Our production of 2-Pyridinecarboxylic Acid, 6-Chloro-5-(Trifluoromethoxy)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.