Description

6-Chloro-3-(Trifluoromethoxy)Picolinic Acid is a high-value, multi-functional heterocyclic building block characterized by its unique trifluoromethoxy and chloro substituents. This compound matters for its critical role in modern agrochemical and pharmaceutical research, where it serves as a key intermediate for synthesizing novel active ingredients with enhanced biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and advanced material sectors seeking to develop new crop protection agents, drug candidates, or specialty chemicals.

Application

• Agrochemical Intermediate: A crucial synthon for the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethoxy group.
• Pharmaceutical Building Block: Used in medicinal chemistry for the synthesis of drug candidates, particularly in areas targeting enzymes or receptors where the picolinic acid scaffold is relevant.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalysis and coordination chemistry due to its carboxylic acid and heterocyclic nitrogen functionalities.
• Material Science Research: Employed in the development of advanced organic materials, such as metal-organic frameworks (MOFs) or functional polymers.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects requiring this specific fluorinated picolinate structure.

Basic Information

Product Name	6-Chloro-3-(Trifluoromethoxy)Picolinic Acid
CAS No.	1221171-83-0
Molecular Formula	C7H3ClF3NO3
Molecular Weight	241.55 g/mol
Synonyms	6-Chloro-3-(trifluoromethoxy)pyridine-2-carboxylic acid; 2-Pyridinecarboxylic acid, 6-chloro-3-(trifluoromethoxy)-; 6-Chloro-3-(trifluoromethoxy)picolinate; 1221171-83-0; 6-Chloro-3-trifluoromethoxypicolinic acid; 3-Trifluoromethoxy-6-chloropicolinic acid
EINECS	Contact for details

Quality Control

Our 6-Chloro-3-(Trifluoromethoxy)Picolinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.