Description

4-(1-Isopropyl-1H-Pyrrolo[2,3-C]Pyridin-3-Yl)Pyrimidin-2-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of targeted therapeutics, particularly within oncology and other disease-modifying areas.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of investigational new drugs and novel small molecule entities.
• Kinase Inhibitor Research: Used in the research and development of potent and selective kinase inhibitors due to its privileged pyrrolopyridine-pyrimidine scaffold.
• Medicinal Chemistry: Employed as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Biochemical Research: Acts as a tool compound or a reference standard in biochemical and pharmacological assays.

Basic Information

Product Name	4-(1-Isopropyl-1H-Pyrrolo[2,3-C]Pyridin-3-Yl)Pyrimidin-2-Ol
CAS No.	1221153-86-1
Molecular Formula	C14H14N4O
Molecular Weight	254.29 g/mol
Synonyms	4-(1-Isopropyl-1H-pyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-ol; 2-Pyrimidinol, 4-(1-isopropyl-1H-pyrrolo[2,3-c]pyridin-3-yl)-; 4-(1-Isopropyl-1H-pyrrolo[2,3-c]pyridin-3-yl)-2-pyrimidinol; 4-(1-Isopropyl-1H-pyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2(1H)-one (tautomer); 1H-Pyrrolo[2,3-c]pyridine, 4-(1-isopropyl-1H-pyrrolo[2,3-c]pyridin-3-yl)-2(1H)-pyrimidinone; CAS 1221153-86-1
EINECS	Contact for details

Quality Control

Our 4-(1-Isopropyl-1H-Pyrrolo[2,3-C]Pyridin-3-Yl)Pyrimidin-2-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The material is moisture-sensitive (hygroscopic); ensure containers are sealed under inert atmosphere after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.