Description

3-Cyclopropyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value, organoboron building block essential for modern synthetic chemistry, particularly in cross-coupling reactions. Its core value lies in enabling the efficient and precise construction of complex molecular architectures, which is critical for research and development in advanced material and life sciences. This compound is primarily needed by pharmaceutical researchers, agrochemical developers, and material scientists for creating novel active ingredients and functional molecules. We supply this critical intermediate with a focus on consistent purity and reliable global availability to support your most demanding projects.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially those containing substituted pyridine and cyclopropyl motifs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific, complex heterocyclic structures.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology Probes: Employed in the synthesis of tagged molecules and probes for studying biological pathways and target engagement.
• Catalyst Ligand Development: The pyridine-boronic ester functionality can be utilized to develop novel ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs serving the pharmaceutical and specialty chemical industries.

Basic Information

Item	Details
Product Name	3-Cyclopropyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1220696-43-4
Molecular Formula	C14H20BNO2
Molecular Weight	245.13 g/mol
Synonyms	3-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyclopropylpyridine; 3-Cyclopropylpyridine-5-boronic acid pinacol ester; (3-Cyclopropyl-5-pyridinyl)boronic acid pinacol ester; 1220696-43-4; 3-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolanyl)pyridine
EINECS	Contact for details

Quality Control

Every batch of 3-Cyclopropyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. Our quality assurance protocols include HPLC, NMR, and MS analysis to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, ensuring full traceability and compliance with your internal quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.