Description

4-(Pyrrolidin-3-Yloxy)-Pyridine Dihydrochloride is a high-purity, non-natural amino acid derivative and a versatile organic building block. This compound matters as a critical intermediate in modern pharmaceutical research and development, particularly for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the creation of targeted small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to modify pharmacokinetic properties.
• Chemical Biology: Serves as a building block for designing molecular probes and inhibitors to study biological pathways.
• Process Chemistry: Employed in route scouting and scale-up synthesis for Active Pharmaceutical Ingredient (API) manufacturing.
• Library Synthesis: A valuable component for generating diverse compound libraries in high-throughput screening campaigns.
• Academic Research: Utilized in universities and institutes for fundamental organic synthesis and methodological studies.

Basic Information

Product Name	4-(Pyrrolidin-3-Yloxy)-Pyridine Dihydrochloride
CAS No.	1220040-28-7
Molecular Formula	C9H13N2O•2HCl
Molecular Weight	241.13 g/mol
Synonyms	4-(3-Pyrrolidinyloxy)pyridine dihydrochloride; 4-(Pyrrolidin-3-yloxy)pyridine hydrochloride (1:2); Pyridine, 4-(3-pyrrolidinyloxy)-, dihydrochloride; 4-(3-Pyrrolidinoxy)pyridine Dihydrochloride; 4-(N-Pyrrolidin-3-yloxy)pyridine 2HCl; 1220040-28-7
EINECS	Contact for details

Quality Control

Our 4-(Pyrrolidin-3-Yloxy)-Pyridine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions (e.g., nitrogen atmosphere) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.