Description

2-(3-Pyrrolidinyloxy)-Pyridine Hydrochloride is a high-purity organic salt compound, primarily utilized as a key pharmaceutical intermediate. Its value lies in its role as a sophisticated building block for the synthesis of complex active pharmaceutical ingredients (APIs). This product is essential for research and development laboratories, process chemists, and manufacturers in the pharmaceutical and fine chemical industries seeking reliable, high-quality intermediates for advanced drug discovery and production programs.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Chemical Synthesis: Used in research-scale and pilot-scale organic synthesis for constructing complex molecular architectures containing pyridine and pyrrolidine motifs.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Process Development: Employed in the development and scale-up of synthetic routes for active pharmaceutical ingredients (APIs).
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	2-(3-Pyrrolidinyloxy)-Pyridine Hydrochloride
CAS No.	1220039-88-2
Molecular Formula	C9H13ClN2O
Molecular Weight	200.67 g/mol
Synonyms	2-[(3-Pyrrolidinyl)oxy]pyridine hydrochloride; 2-(Pyrrolidin-3-yloxy)pyridine HCl; Pyridine, 2-(3-pyrrolidinyloxy)-, hydrochloride; 3-(Pyridin-2-yloxy)pyrrolidine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(3-Pyrrolidinyloxy)-Pyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods (IR, NMR), and residual solvent analysis to ensure it meets exacting standards for pharmaceutical intermediate use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.