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1-(3-Fluoro-2-Methoxyphenyl)Ethanol CAS NO 1220039-38-2


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CAS No.:1220039-38-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-(3-Fluoro-2-Methoxyphenyl)Ethanol is a fluorinated aromatic alcohol building block of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the development of active pharmaceutical ingredients (APIs) and complex agrochemicals. Pharmaceutical R&D teams and fine chemical manufacturers need it for constructing molecules where the specific substitution pattern of fluorine and methoxy groups is critical for biological activity and metabolic stability.

Application

  • Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
  • Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorine atom enhances bioactivity and environmental persistence.
  • Liquid Crystal Materials: Serves as a precursor for fluorinated mesogens used in display technologies, contributing to improved thermal stability and optical properties.
  • Organic Ligand Preparation: Employed in the development of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
  • Flavor & Fragrance Chemistry: Acts as a building block for synthesizing complex, fluorinated aromatic compounds used in high-value fragrance ingredients.
  • Academic & Industrial Research: A valuable reagent for methodological studies in fluorination chemistry and asymmetric synthesis.

Basic Information

Product Name 1-(3-Fluoro-2-Methoxyphenyl)Ethanol
CAS No. 1220039-38-2
Molecular Formula C9H11FO2
Molecular Weight 170.18 g/mol
Synonyms 1-(3-Fluoro-2-methoxyphenyl)ethan-1-ol; (3-Fluoro-2-methoxyphenyl)methylcarbinol; α-Methyl-3-fluoro-2-methoxybenzyl alcohol; 2-Methoxy-3-fluoro-α-methylbenzyl alcohol; 1-(3-Fluoro-2-methoxyphenyl)ethyl alcohol; 3-Fluoro-2-methoxy-α-methylbenzyl alcohol; 1-(3-Fluoro-2-methoxyphenyl)ethanol; FMPE
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Quality Control

Our production of 1-(3-Fluoro-2-Methoxyphenyl)Ethanol adheres to strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure compliance with exacting customer specifications for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage under an inert atmosphere (nitrogen or argon), please contact our technical team for specific recommendations.

Specification

Item Specification
Appearance Colorless to pale yellow liquid or low-melting solid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Chiral Purity (Chiral HPLC) ≥ 99.0% ee (typical, specific grade available)
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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