Description

n-(2-Hydroxy-1,1-Dimethylethyl)-4,5,6,7-Tetra-Hydro-1H-Pyrazolo[4,3-C]Pyridine-3-Carboxamide Hcl is a high-purity pharmaceutical intermediate and research chemical. This compound is valued for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research. It is essential for pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel therapeutic agents, especially for neurological and psychiatric targets.
• Medicinal Chemistry Research: Used as a core scaffold or derivatization point for structure-activity relationship (SAR) studies and lead optimization.
• API Development: Serves as a building block in the process development and scale-up of candidate drug molecules.
• Biochemical Research: Potential use as a tool compound or ligand in biochemical assays and target validation studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic and pharmacological research.

Basic Information

Product Name	n-(2-Hydroxy-1,1-Dimethylethyl)-4,5,6,7-Tetra-Hydro-1H-Pyrazolo[4,3-C]Pyridine-3-Carboxamide Hydrochloride
CAS No.	1220030-25-0
Molecular Formula	C13H21N4O2 • HCl
Molecular Weight	300.79 g/mol (Free base: 265.33 g/mol)
Synonyms	4,5,6,7-Tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxamide, N-(2-hydroxy-1,1-dimethylethyl)-, hydrochloride; 1-(2-Hydroxy-1,1-dimethylethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxamide HCl; 1220030-25-0; Pyrazolopyridine carboxamide derivative HCl; Tert-butyl hydroxyethyl pyrazolopyridine carboxamide hydrochloride
EINECS	Contact for details

Quality Control

Our n-(2-Hydroxy-1,1-Dimethylethyl)-4,5,6,7-Tetra-Hydro-1H-Pyrazolo[4,3-C]Pyridine-3-Carboxamide Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity (typically >97% by HPLC), residual solvents, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.