Description

3-(Cyclobutylmethoxy)Piperidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate and building block of significant interest in modern organic synthesis. Its unique molecular architecture, featuring a piperidine core modified with a cyclobutylmethoxy substituent, makes it a valuable scaffold for medicinal chemistry research and development. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the creation of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization programs.
• Process Chemistry Development: Used in route scouting and scale-up studies for the production of target molecules under Good Manufacturing Practice (GMP) conditions.
• Chemical Biology Probes: Employed in the development of tool compounds for investigating biological pathways and target validation.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.
• Academic Research: Utilized in university and institutional laboratories for methodological development and exploring new chemical spaces.

Basic Information

Product Name	3-(Cyclobutylmethoxy)Piperidine Hydrochloride
CAS No.	1220020-94-9
Molecular Formula	C10H20ClNO
Molecular Weight	205.73 g/mol
Synonyms	3-(Cyclobutylmethoxy)piperidine HCl; 3-(Cyclobutylmethoxy)piperidine hydrochloride; Piperidine, 3-(cyclobutylmethoxy)-, hydrochloride (1:1); 3-Cyclobutylmethoxypiperidine hydrochloride; 1220020-94-9; 3-(Cyclobutylmethoxy)piperidine monohydrochloride
EINECS	Contact for details

Quality Control

Our 3-(Cyclobutylmethoxy)Piperidine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes comprehensive analytical characterization, including identity confirmation, purity assessment, and impurity profiling using advanced techniques such as HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.