Description

4-(6-Chloro-2-Pyridinyl)-2-Piperazinone is a specialized heterocyclic organic compound that serves as a critical building block in advanced chemical synthesis. This high-purity intermediate is valued for its unique molecular structure, which is essential for constructing complex pharmacologically active molecules. It is primarily utilized by research institutions and pharmaceutical development companies engaged in the creation of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its pyridine-piperazinone core.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the multi-step synthesis of complex target molecules for clinical and commercial scale production.
• Ligand and Catalyst Development: Utilized in organometallic chemistry for creating novel ligands and catalysts.

Basic Information

Product Name	4-(6-Chloro-2-Pyridinyl)-2-Piperazinone
CAS No.	1220017-61-7
Molecular Formula	C9H10ClN3O
Molecular Weight	211.65 g/mol
Synonyms	2-Piperazinone, 4-(6-chloro-2-pyridinyl)-; 4-(6-Chloropyridin-2-yl)piperazin-2-one; 6-Chloro-2-(2-oxopiperazin-1-yl)pyridine; 1-(6-Chloropyridin-2-yl)piperazin-2-one; 4-(6-Chloro-2-pyridyl)-2-piperazinone
EINECS	Contact for details

Quality Control

Our 4-(6-Chloro-2-Pyridinyl)-2-Piperazinone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.