Description

2-[Methyl(Tetrahydro-2H-Pyran-4-Ylmethyl)Amino]-Isonicotinic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyranylmethylamino-substituted isonicotinic acid structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting complex disease pathways. It is primarily utilized by pharmaceutical R&D laboratories, custom synthesis providers, and agrochemical innovators seeking to develop new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-infective research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new-generation pesticides and herbicides.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Academic & Institutional Research: Employed in university and institutional labs for exploratory organic synthesis and chemical biology studies.

Basic Information

Product Name	2-[Methyl(Tetrahydro-2H-Pyran-4-Ylmethyl)Amino]-Isonicotinic Acid
CAS No.	1219981-32-4
Molecular Formula	C14H20N2O3
Molecular Weight	264.32 g/mol
Synonyms	2-[(Methyl)(tetrahydro-2H-pyran-4-ylmethyl)amino]isonicotinic acid; 2-[Methyl(tetrahydro-2H-pyran-4-ylmethyl)amino]pyridine-4-carboxylic acid; 4-Pyridinecarboxylic acid, 2-[(methyl)(tetrahydro-2H-pyran-4-ylmethyl)amino]-; 1219981-32-4; 2-(Methyl(tetrahydro-2H-pyran-4-ylmethyl)amino)isonicotinic acid; Methyl(tetrahydro-2H-pyran-4-ylmethyl)amino-isonicotinic acid derivative.
EINECS	Contact for details

Quality Control

Our 2-[Methyl(Tetrahydro-2H-Pyran-4-Ylmethyl)Amino]-Isonicotinic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with the standards expected for advanced pharmaceutical intermediates in global supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to maintain stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.