Description

1-(5-Bromo-4-Methylpyridin-2-Yl)-4-Methylpiperazine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyridine-piperazine hybrid structure. This compound is of significant commercial value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought after by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially in oncology and central nervous system (CNS) therapeutic research.
• Chemical Synthesis Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization due to its modifiable bromo and methyl substituents.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in catalytic systems or for metal-organic framework (MOF) construction.
• Agrochemical Research: Employed in the development of new-generation pesticides and herbicides where its heterocyclic core provides specific bioactivity.
• Material Science Research: Investigated for incorporation into organic electronic materials or as a monomer for functional polymers.

Basic Information

Product Name	1-(5-Bromo-4-Methylpyridin-2-Yl)-4-Methylpiperazine
CAS No.	1219967-32-4
Molecular Formula	C11H16BrN3
Molecular Weight	270.17 g/mol
Synonyms	4-Methyl-1-(5-bromo-4-methyl-2-pyridinyl)piperazine; 1-(5-Bromo-4-methylpyridin-2-yl)-4-methylpiperazine; 5-Bromo-4-methyl-2-(4-methylpiperazin-1-yl)pyridine; 2-(4-Methylpiperazin-1-yl)-5-bromo-4-methylpyridine
EINECS	Contact for details

Quality Control

Our production of 1-(5-Bromo-4-Methylpyridin-2-Yl)-4-Methylpiperazine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR) to confirm identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting compliance in cGMP and ISO 9001 environments for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.