Description

4,6-Difluoro-n-(Pyridin-4-Ylmethyl)Benzo[D]Thiazol-2-Amine is a high-purity, advanced pharmaceutical intermediate featuring a benzothiazole core functionalized with fluorine and a pyridinylmethylamine group. This compound matters for its critical role as a key building block in the synthesis of novel, targeted small-molecule therapeutics, particularly in oncology and kinase inhibitor research. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material to develop next-generation drug candidates with improved potency and selectivity profiles.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel kinase inhibitors and targeted cancer therapies.
• Chemical Biology Research: Used as a molecular scaffold or probe in drug discovery and structure-activity relationship (SAR) studies.
• Agrochemical Development: Serves as a building block for creating new active ingredients with potential fungicidal or herbicidal properties.
• Material Science: Potential precursor for functionalized organic materials and ligands in catalytic systems.
• Academic & Contract Research: Employed in universities and CROs for medicinal chemistry projects and methodological development.

Basic Information

Product Name	4,6-Difluoro-n-(Pyridin-4-Ylmethyl)Benzo[D]Thiazol-2-Amine
CAS No.	1219845-00-7
Molecular Formula	C₁₄H₁₀F₂N₄S
Molecular Weight	304.32 g/mol
Synonyms	4,6-Difluoro-N-(pyridin-4-ylmethyl)-1,3-benzothiazol-2-amine; 2-Amino-4,6-difluorobenzothiazole N-(4-Pyridylmethyl) Derivative; 4,6-Difluoro-2-[(4-pyridinylmethyl)amino]benzothiazole; 1219845-00-7; 4,6-Difluoro-N-(4-pyridinylmethyl)-2-benzothiazolamine; Benzo[d]thiazol-2-amine, 4,6-difluoro-N-(4-pyridinylmethyl)-; 4,6-Difluoro-N-(pyridin-4-ylmethyl)benzo[d]thiazol-2-amine
EINECS	Contact for details

Quality Control

Our 4,6-Difluoro-n-(Pyridin-4-Ylmethyl)Benzo[D]Thiazol-2-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and KF titration for moisture content. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.