Description

1-{[2-(2-Fluorophenyl)-4-Methyl-1,3-Thiazol-5-Yl]Carbonyl}Piperidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel drug candidates targeting central nervous system and metabolic disorders. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, particularly for neurological and psychiatric targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its unique thiazole-piperidine scaffold.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the multi-step synthesis of complex final APIs for preclinical and clinical studies.
• Chemical Biology Probes: Employed in the development of tool compounds for investigating biological pathways and target validation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Used in university and institutional labs for exploratory research in organic synthesis and drug discovery.

Basic Information

Product Name	1-{[2-(2-Fluorophenyl)-4-Methyl-1,3-Thiazol-5-Yl]Carbonyl}Piperidine-3-Carboxylic Acid
CAS No.	1219566-70-7
Molecular Formula	C17H17FN2O3S
Molecular Weight	348.39 g/mol
Synonyms	1-[(2-(2-Fluorophenyl)-4-methyl-1,3-thiazol-5-yl)carbonyl]piperidine-3-carboxylic acid; 3-Piperidinecarboxylic acid, 1-[[2-(2-fluorophenyl)-4-methyl-5-thiazolyl]carbonyl]-; 1-{[2-(2-Fluorophenyl)-4-methyl-1,3-thiazol-5-yl]carbonyl}piperidine-3-carboxylic acid; 1219566-70-7; 1-((2-(2-Fluorophenyl)-4-methylthiazole-5-carbonyl)piperidine-3-carboxylic acid; 1-[(2-(2-Fluorophenyl)-4-methylthiazol-5-yl)carbonyl]piperidine-3-carboxylic acid; 1-{[2-(2-Fluorophenyl)-4-methyl-1,3-thiazol-5-yl]carbonyl}-3-piperidinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 1-{[2-(2-Fluorophenyl)-4-Methyl-1,3-Thiazol-5-Yl]Carbonyl}Piperidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment. We support development and commercial projects with material suitable for research use and can supply material manufactured under cGMP guidelines for advanced clinical stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.