Description

Propyl 7-Amino-6,7,8,9-Tetrahydropyrido[1,2-A]Indole-10-Acetate is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1218918-73-0. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) due to its unique fused heterocyclic structure. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within the fields of oncology and central nervous system (CNS) disorders.

Application

This specialized intermediate serves as a key building block in sophisticated organic synthesis. Its primary applications include:

• Pharmaceutical Intermediate: Core precursor in the synthesis of novel drug candidates targeting specific biological pathways.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Synthesis: Integral component in multi-step synthetic routes for complex target molecules.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production.
• Academic Research: Employed in university and institutional labs for exploratory synthetic chemistry and pharmacological research.

Basic Information

Item	Details
Product Name	Propyl 7-Amino-6,7,8,9-Tetrahydropyrido[1,2-A]Indole-10-Acetate
CAS No.	1218918-73-0
Molecular Formula	C17H20N2O2
Molecular Weight	284.36 g/mol
Synonyms	7-Amino-6,7,8,9-tetrahydropyrido[1,2-a]indole-10-acetic acid propyl ester; Propyl 7-amino-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-ylacetate; 10-Acetic acid, 7-amino-6,7,8,9-tetrahydropyrido[1,2-a]indol-, propyl ester; 1218918-73-0; Propyl ester of 7-Amino-6,7,8,9-tetrahydropyrido[1,2-a]indole-10-acetic acid
EINECS	Contact for details

Quality Control

Our Propyl 7-Amino-6,7,8,9-Tetrahydropyrido[1,2-A]Indole-10-Acetate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically by HPLC), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.