Description

Lde-225 Diphosphate is a high-purity, specialized phosphate derivative of the Lde-225 compound, identified by CAS No. 1218778-77-8. This chemical is engineered to provide enhanced stability and solubility for advanced research and development applications. It serves as a critical intermediate and active component for pharmaceutical discovery, particularly in targeted therapeutic areas, and for sophisticated biochemical research. Our supply ensures consistent quality and reliable availability for industrial and institutional laboratories worldwide.

Application

• Pharmaceutical Research & Development: Utilized as a key intermediate or reference standard in the synthesis and screening of novel drug candidates.
• Biochemical Assays: Serves as a substrate or modulator in enzymatic and receptor-binding studies to investigate biological pathways.
• Preclinical Studies: Employed in formulation development and pharmacokinetic/pharmacodynamic (PK/PD) modeling for potential therapeutics.
• Chemical Synthesis: Acts as a building block for the preparation of more complex molecules in medicinal chemistry.
• Analytical Reference Standard: Used for method development, validation, and quality control in analytical laboratories (HPLC, LC-MS).
• Academic Research: Supports investigative work in universities and research institutes focusing on molecular biology and pharmacology.

Basic Information

Product Name	Lde-225 Diphosphate
CAS No.	1218778-77-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	LDE225 Diphosphate; LDE-225 diphosphate salt; NVP-LDE225 Diphosphate; Sonidegib Diphosphate; Erismodegib Diphosphate; (2S)-N-[6-Methoxy-8-[(2,2,6,6-tetramethyl-4-piperidyl)oxy]-3,4-dihydro-2H-1-benzopyran-2-yl]-2-methyl-2-{[(1-propanoylpiperidin-4-yl)carbonyl]amino}propanamide diphosphate
EINECS	Contact for details

Quality Control

Our Lde-225 Diphosphate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-grade specifications for research use. A comprehensive Certificate of Analysis (COA) detailing purity, residual solvents, and other critical parameters is provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.