Description

(S)-tert-Butyl 3-[(Pyridin-4-Ylmethyl)Amino]Piperidine-1-Carboxylate is a high-purity chiral piperidine derivative, serving as a critical building block in modern pharmaceutical synthesis. Its value lies in its role as a sophisticated intermediate for constructing complex molecules with specific stereochemistry, which is essential for developing targeted therapeutics. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and process development of new active pharmaceutical ingredients (APIs), particularly in areas like oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, especially for kinase inhibitors and receptor modulators.
• Chemical Biology Probe Synthesis: Used to create labeled or modified compounds for studying biological pathways and target engagement.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in enantioselective synthesis.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale manufacturing of advanced pharmaceutical intermediates.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific projects requiring bespoke chiral building blocks.

Basic Information

Item	Details
Product Name	(S)-tert-Butyl 3-[(Pyridin-4-Ylmethyl)Amino]Piperidine-1-Carboxylate
CAS No.	1217722-00-3
Molecular Formula	C16H25N3O2
Molecular Weight	291.39 g/mol
Synonyms	(S)-1-Boc-3-[(4-Pyridylmethyl)amino]piperidine; (S)-tert-Butyl 3-((pyridin-4-ylmethyl)amino)piperidine-1-carboxylate; (S)-N-[(Pyridin-4-yl)methyl]-1-(tert-butoxycarbonyl)piperidin-3-amine; 1-Piperidinecarboxylic acid, 3-[(4-pyridinylmethyl)amino]-, 1,1-dimethylethyl ester, (3S)-; (3S)-3-{[(Pyridin-4-yl)methyl]amino}-1-piperidinecarboxylic acid tert-butyl ester; (S)-1-Boc-3-(4-picolylamino)piperidine; (S)-3-((4-Picolyl)amino)-1-Boc-piperidine
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl 3-[(Pyridin-4-Ylmethyl)Amino]Piperidine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC to ensure enantiomeric purity and identity confirmation via spectroscopic methods. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.