Description

2-(4-Iodopyridin-2-Yl)-2-Methylpropanenitrile is a specialized organic building block featuring a pyridine core functionalized with an iodine atom and a nitrile group. This compound matters as a versatile intermediate for constructing complex molecules in pharmaceutical and agrochemical research, enabling critical carbon-carbon and carbon-heteroatom bond formations. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor and other small molecule therapeutic programs.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides requiring halogenated pyridine scaffolds.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Functional Material Development: Employed in the research of organic electronic materials and liquid crystals.
• Chemical Biology Probes: Useful for synthesizing tagged molecules for studying biological pathways and target engagement.

Basic Information

Product Name	2-(4-Iodopyridin-2-Yl)-2-Methylpropanenitrile
CAS No.	1217486-73-1
Molecular Formula	C9H9IN2
Molecular Weight	272.09 g/mol
Synonyms	2-(4-Iodo-2-pyridinyl)-2-methylpropanenitrile; 2-Methyl-2-(4-iodopyridin-2-yl)propanenitrile; Propanenitrile, 2-(4-iodo-2-pyridinyl)-2-methyl-; 4-Iodo-2-(2-cyano-2-propyl)pyridine; 2-(4-Iodopyridin-2-yl)-2-methylpropionitrile; 1217486-73-1; AI3-32833
EINECS	Contact for details

Quality Control

Our 2-(4-Iodopyridin-2-Yl)-2-Methylpropanenitrile is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C for long-term stability. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.