Description

1-[6-(3-Fluorophenyl)Pyridin-3-Yl]Ethanone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its specific molecular architecture enables precise structural modifications. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate a fluorinated bipyridyl moiety into their target molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of advanced organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	1-[6-(3-Fluorophenyl)Pyridin-3-Yl]Ethanone
CAS No.	1216541-77-3
Molecular Formula	C13H10FNO
Molecular Weight	215.22 g/mol
Synonyms	1-[6-(3-Fluorophenyl)-3-pyridinyl]ethanone; 3'-Fluoro-6-acetyl-[3,3'-bipyridine]; 1-(6-(3-Fluorophenyl)pyridin-3-yl)ethan-1-one; 3-Acetyl-6-(3-fluorophenyl)pyridine; Ethanone, 1-[6-(3-fluorophenyl)-3-pyridinyl]-; 6-(3-Fluorophenyl)nicotinyl methyl ketone; 3-Pyridinyl, 6-(3-fluorophenyl)-, ethanone deriv.
EINECS	Contact for details

Quality Control

Our 1-[6-(3-Fluorophenyl)Pyridin-3-Yl]Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.