Description

[2-(4-Bromo-Phenyl)-6-Trifluoromethyl-Imidazo[1,2-A]Pyridin-3-Yl]-Methanol is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound matters for its unique molecular architecture, which combines a brominated phenyl group, a trifluoromethyl moiety, and an imidazopyridine core with a reactive hydroxymethyl handle, enabling precise structural modifications. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients, particularly in the development of kinase inhibitors and other targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, especially in oncology and CNS disorders.
• Kinase Inhibitor Scaffold: Serves as a privileged core structure for designing and synthesizing potent and selective kinase inhibitors.
• Agrochemical Research: Used in the discovery of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic framework.
• Material Science Chemistry: Acts as a building block for synthesizing advanced organic electronic materials and ligands for catalysis.
• Chemical Biology Probe Development: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and libraries for high-throughput screening.

Basic Information

Product Name	[2-(4-Bromo-Phenyl)-6-Trifluoromethyl-Imidazo[1,2-A]Pyridin-3-Yl]-Methanol
CAS No.	1216488-91-3
Molecular Formula	C15H10BrF3N2O
Molecular Weight	371.16 g/mol
Synonyms	(2-(4-Bromophenyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl)methanol; 3-(Hydroxymethyl)-2-(4-bromophenyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridine; 2-(4-Bromophenyl)-6-trifluoromethylimidazo[1,2-a]pyridine-3-methanol; [2-(4-Bromophenyl)-6-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]methanol; Imidazo[1,2-a]pyridine-3-methanol, 2-(4-bromophenyl)-6-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Every batch of [2-(4-Bromo-Phenyl)-6-Trifluoromethyl-Imidazo[1,2-A]Pyridin-3-Yl]-Methanol is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development use. Comprehensive analytical characterization, including HPLC, NMR, and MS, is performed to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.