Description

6-Bromo-3,8-Dimethylimidazo[1,2-A]Pyridine is a high-value brominated heterocyclic building block, specifically an imidazopyridine derivative, essential for advanced organic synthesis and pharmaceutical research. Its core value lies in its unique molecular scaffold, which serves as a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the synthesis of novel pesticides and herbicides, leveraging its heterocyclic structure to create compounds with specific biological activity.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways due to its modifiable bromo group.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Buchwald-Hartwig) to form carbon-carbon and carbon-heteroatom bonds.
• Library Synthesis for High-Throughput Screening: Employed in combinatorial chemistry to generate diverse compound libraries for biological screening and hit identification.

Basic Information

Product Name	6-Bromo-3,8-Dimethylimidazo[1,2-A]Pyridine
CAS No.	1216185-38-4
Molecular Formula	C9H9BrN2
Molecular Weight	225.09 g/mol
Synonyms	6-Bromo-3,8-dimethylimidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 6-bromo-3,8-dimethyl-; 3,8-Dimethyl-6-bromoimidazo[1,2-a]pyridine; 6-Bromo-3,8-dimethyl-imidazo[1,2-a]pyridine; 1216185-38-4
EINECS	Contact for details

Quality Control

Our 6-Bromo-3,8-Dimethylimidazo[1,2-A]Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.