Description

Methyl 3-Chloro-2-Fluoroisonicotinate is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its unique halogenated structure, which enables precise molecular modifications essential for developing novel active ingredients. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of complex molecules, including potential active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced pesticides and herbicides, leveraging its halogenated pyridine core.
• Chemical Research: Serves as a versatile building block in academic and industrial laboratories for constructing complex heterocyclic compounds.
• Material Science: Potential application in the synthesis of specialty chemicals and functional materials requiring fluorinated aromatic components.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule development and scale-up projects.

Basic Information

Product Name	Methyl 3-Chloro-2-Fluoroisonicotinate
CAS No.	1214385-95-1
Molecular Formula	C7H5ClFNO2
Molecular Weight	189.57 g/mol
Synonyms	3-Chloro-2-fluoropyridine-4-carboxylic acid methyl ester; Methyl 3-chloro-2-fluoro-4-pyridinecarboxylate; 2-Fluoro-3-chloroisonicotinic acid methyl ester; 4-Pyridinecarboxylic acid, 3-chloro-2-fluoro-, methyl ester; Methyl 2-fluoro-3-chloroisonicotinate; 3-Chloro-2-fluoro-4-(methoxycarbonyl)pyridine
EINECS	Contact for details

Quality Control

Our Methyl 3-Chloro-2-Fluoroisonicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.