Description

5,6-Dibromonicotinonitrile is a high-value brominated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it an indispensable intermediate for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This compound is essential for chemists and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and functional materials who require reliable, high-purity intermediates to ensure successful downstream reactions and final product quality.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the dibromo-nicotinonitrile scaffold imparts specific biological activity.
• Material Science Research: Serves as a building block for creating functional organic materials, including ligands for catalysis and monomers for specialty polymers.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and tags for studying biological systems.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to introduce complex substituents onto the pyridine ring.
• Heterocyclic Chemistry: Fundamental starting material for the preparation of a wide array of fused and substituted nitrogen-containing heterocycles.

Basic Information

Product Name	5,6-Dibromonicotinonitrile
CAS No.	1214384-33-4
Molecular Formula	C6H2Br2N2
Molecular Weight	261.90 g/mol
Synonyms	5,6-Dibromo-3-cyanopyridine; 3-Cyano-5,6-dibromopyridine; Nicotinonitrile, 5,6-dibromo-; 5,6-Dibromopyridine-3-carbonitrile; 2-Bromo-5-cyano-3,6-dihydropyridine (tautomer); 5,6-Dibromo-3-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Every batch of 5,6-Dibromonicotinonitrile is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.