Description

3-Methoxy-6-(Trifluoromethyl)Picolinonitrile is a high-value, multi-functional heterocyclic building block characterized by its picolinonitrile core, methoxy substituent, and trifluoromethyl group. This compound is strategically important for its role in facilitating the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Ligand and Catalyst Precursor: Serves as a starting material for the synthesis of specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors and light-emitting components, due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Methoxy-6-(Trifluoromethyl)Picolinonitrile
CAS No.	1214383-70-6
Molecular Formula	C8H5F3N2O
Molecular Weight	202.13 g/mol
Synonyms	3-Methoxy-6-(trifluoromethyl)pyridine-2-carbonitrile; 2-Cyano-3-methoxy-6-(trifluoromethyl)pyridine; 6-(Trifluoromethyl)-3-methoxypicolinonitrile; 3-Methoxy-6-trifluoromethylpicolinonitrile; 2-Pyridinecarbonitrile, 3-methoxy-6-(trifluoromethyl)-; 3-Methoxy-6-(trifluoromethyl)-2-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Our 3-Methoxy-6-(Trifluoromethyl)Picolinonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.