Description

Methyl 2,5-Dibromo-4-Pyridinecarboxylate is a high-purity, multi-functional brominated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its reactive halogen sites and ester functionality, enabling precise molecular construction for complex target molecules. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for constructing complex chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as electron-transport layers or components for OLEDs and perovskites.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create biaryl and complex heterocyclic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	Methyl 2,5-Dibromo-4-Pyridinecarboxylate
CAS No.	1214378-73-0
Molecular Formula	C7H5Br2NO2
Molecular Weight	294.93 g/mol
Synonyms	4-Pyridinecarboxylic acid, 2,5-dibromo-, methyl ester; Methyl 2,5-dibromopyridine-4-carboxylate; 2,5-Dibromo-4-(methoxycarbonyl)pyridine; Methyl 2,5-dibromopyridine-4-carboxylic acid ester; 2,5-Dibromo-4-pyridinecarboxylic acid methyl ester; Methyl 2,5-dibromopyridine-4-carboxylate; Methyl 2,5-dibromo-isonicotinate
EINECS	Contact for details

Quality Control

Our Methyl 2,5-Dibromo-4-Pyridinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.