Description

3-Pyridinecarboxylic Acid, 4-Fluoro-, Methyl Ester is a high-purity fluorinated pyridine derivative, a key building block in advanced organic synthesis. This compound is valued for its role in introducing both the pyridine core and a fluorine substituent, which are critical for modulating the biological activity and physicochemical properties of target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of fluorinated drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides where the fluorine atom enhances metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and liquid crystals.
• Chemical Biology Probes: Utilized to create fluorinated analogs of natural products for mechanistic and metabolic pathway studies.

Basic Information

Product Name	3-Pyridinecarboxylic Acid, 4-Fluoro-, Methyl Ester
CAS No.	1214375-37-7
Molecular Formula	C8H8FNO2
Molecular Weight	169.15 g/mol
Synonyms	Methyl 4-Fluoronicotinate; 4-Fluoronicotinic Acid Methyl Ester; 4-Fluoro-3-pyridinecarboxylic Acid Methyl Ester; Methyl 4-Fluoro-3-pyridinecarboxylate; 4-Fluoropyridine-3-carboxylic Acid Methyl Ester; 3-Carbomethoxy-4-fluoropyridine; 1214375-37-7
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarboxylic Acid, 4-Fluoro-, Methyl Ester is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.