Description

Methyl 3-Bromo-5-Chloropyridine-2-Carboxylate is a high-purity, multi-halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it a versatile intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated pyridine motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the halogenated pyridine core provides specific bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials and liquid crystals due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring precise halogen functionalization on a pyridine ring.

Basic Information

Product Name	Methyl 3-Bromo-5-Chloropyridine-2-Carboxylate
CAS No.	1214362-45-4
Molecular Formula	C7H5BrClNO2
Molecular Weight	250.48 g/mol
Synonyms	Methyl 3-bromo-5-chloropicolinate; 3-Bromo-5-chloropyridine-2-carboxylic acid methyl ester; 2-Pyridinecarboxylic acid, 3-bromo-5-chloro-, methyl ester; 3-Bromo-5-chloro-2-pyridinecarboxylic acid methyl ester; Methyl 3-bromo-5-chloro-2-pyridinecarboxylate; 1214362-45-4; Methyl 3-bromo-5-chloropicolinate
EINECS	Contact for details

Quality Control

Our Methyl 3-Bromo-5-Chloropyridine-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our commitment to quality supports applications requiring high-purity intermediates under cGMP and ISO standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.