Description

(5-Bromo-2-(Trifluoromethyl)Phenyl)Methanol CAS NO 1214349-54-8 is a high-value fluorinated aromatic building block essential for advanced organic synthesis. Its unique structure, combining bromo and trifluoromethyl substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances bioavailability and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Incorporated into the synthesis of specialty polymers, liquid crystals, and organic electronic materials to modify solubility and electronic properties.
• Chemical Biology Probes: Utilized in the creation of molecular probes and tags for studying biological processes and target engagement.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.

Basic Information

Product Name	(5-Bromo-2-(Trifluoromethyl)Phenyl)Methanol
CAS No.	1214349-54-8
Molecular Formula	C8H6BrF3O
Molecular Weight	255.04 g/mol
Synonyms	[5-Bromo-2-(trifluoromethyl)phenyl]methanol; (5-Bromo-2-(trifluoromethyl)phenyl)carbinol; 5-Bromo-α,α,α-trifluoro-o-tolyl alcohol; 2-(Trifluoromethyl)-5-bromobenzyl alcohol; 5-Bromo-2-trifluoromethylbenzyl alcohol; 1-(5-Bromo-2-(trifluoromethyl)phenyl)methanol; Benzenemethanol, 5-bromo-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our (5-Bromo-2-(Trifluoromethyl)Phenyl)Methanol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.