Description

4-(3-Fluorophenyl)Pyridine-2-Carboxylic Acid is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular architecture, which combines a fluorinated aromatic ring with a pyridine carboxylic acid moiety, enabling precise modifications in complex molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand Synthesis: Serves as a versatile starting material for constructing complex ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Advanced Material Development: A building block for creating functionalized polymers and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects requiring fluorinated heterocycles.

Basic Information

Product Name	4-(3-Fluorophenyl)Pyridine-2-Carboxylic Acid
CAS No.	1214349-18-4
Molecular Formula	C12H8FNO2
Molecular Weight	217.20 g/mol
Synonyms	2-Pyridinecarboxylic acid, 4-(3-fluorophenyl)-; 4-(3-Fluorophenyl)picolinic acid; 4-(3-Fluorophenyl)-2-pyridinecarboxylic acid; 3-Fluoro-4-(2-carboxypyridin-4-yl)benzene; 1214349-18-4; 4-(3-Fluorophenyl)picolinate
EINECS	Contact for details

Quality Control

Our production of 4-(3-Fluorophenyl)Pyridine-2-Carboxylic Acid adheres to stringent quality management protocols. Each batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality system is designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled and stored away from direct light. Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.