Description

3-Bromo-2-Iodo-6-(Trifluoromethyl)Pyridine is a high-value, multi-halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine, iodine, and a trifluoromethyl group on the pyridine ring, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products, leveraging the bioactivity imparted by the halogen and trifluoromethyl motifs.
• Material Science Research: Serves as a building block for developing specialty polymers, liquid crystals, and organic electronic materials due to its distinct electronic properties.
• Cross-Coupling Reactions: The bromine and iodine substituents make it an excellent substrate for versatile metal-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Negishi) to form complex biaryl and alkynyl structures.
• Ligand and Catalyst Development: Utilized in the preparation of novel nitrogen-containing ligands for catalysis and coordination chemistry.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological systems.

Basic Information

Item	Details
Product Name	3-Bromo-2-Iodo-6-(Trifluoromethyl)Pyridine
CAS No.	1214348-80-7
Molecular Formula	C6H2BrF3IN
Molecular Weight	361.89 g/mol
Synonyms	3-Bromo-2-iodo-6-(trifluoromethyl)pyridine; 2-Iodo-3-bromo-6-(trifluoromethyl)pyridine; 6-(Trifluoromethyl)-3-bromo-2-iodopyridine; Pyridine, 3-bromo-2-iodo-6-(trifluoromethyl)-; 1214348-80-7
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Iodo-6-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/GC-MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.