Description

3-Pyridinecarboxylic Acid, 2-Chloro-6-Fluoro-, Ethyl Ester is a high-purity fluorinated pyridine derivative, a crucial building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine and chlorine substituents can enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and material science applications.
• Chemical Research: Employed in academic and industrial R&D for method development and exploring new chemical reactions involving halogenated heterocycles.
• Fine Chemical Production: An intermediate in the multi-step synthesis of complex fluorinated fine chemicals and dyes.

Basic Information

Product Name	3-Pyridinecarboxylic Acid, 2-Chloro-6-Fluoro-, Ethyl Ester
CAS No.	1214347-06-4
Molecular Formula	C9H7ClFNO2
Molecular Weight	215.61 g/mol
Synonyms	2-Chloro-6-fluoronicotinic acid ethyl ester; Ethyl 2-chloro-6-fluoropyridine-3-carboxylate; 2-Chloro-6-fluoro-3-pyridinecarboxylic acid ethyl ester; 2-Chloro-6-fluoronicotinic acid ethyl ester; 3-Carbethoxy-2-chloro-6-fluoropyridine; Ethyl 2-chloro-6-fluoronicotinate; 1214347-06-4; 2-Chloro-6-fluoro-pyridine-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarboxylic Acid, 2-Chloro-6-Fluoro-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.