Description

Ethyl 5-Bromo-6-Hydroxypicolinate is a high-purity organic intermediate of significant importance in advanced chemical synthesis. This compound is valued for its functionalized pyridine core, which serves as a versatile building block for constructing complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, leveraging its halogenated heterocyclic structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or light-emitting components, due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific bromo-hydroxypicolinate derivatives.

Basic Information

Product Name	Ethyl 5-Bromo-6-Hydroxypicolinate
CAS No.	1214346-74-3
Molecular Formula	C8H8BrNO3
Molecular Weight	246.06 g/mol
Synonyms	5-Bromo-6-hydroxypyridine-2-carboxylic acid ethyl ester; Ethyl 5-bromo-6-hydroxy-2-pyridinecarboxylate; 2-Pyridinecarboxylic acid, 5-bromo-6-hydroxy-, ethyl ester; 6-Hydroxy-5-bromopicolinic acid ethyl ester; 5-Bromo-6-hydroxypicolinic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Bromo-6-Hydroxypicolinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to reliable supply and batch-to-batch consistency supports your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.