Description

2-Fluoro-6-Iodopyridine is a high-value halogenated pyridine derivative, serving as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it an essential intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as cross-coupling reactions and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry for creating fluorinated and iodinated bioactive molecules.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the halogen atoms contribute to biological activity and metabolic stability.
• Cross-Coupling Reactions: Serves as an excellent substrate for metal-catalyzed reactions like Suzuki, Stille, and Negishi couplings to form biaryl and other complex structures.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and functional materials.
• Chemical Research & Development: A valuable reagent for method development and exploring new synthetic pathways in academic and industrial R&D laboratories.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and liquid crystals.

Basic Information

Product Name	2-Fluoro-6-Iodopyridine
CAS No.	1214345-93-3
Molecular Formula	C5H3FIN
Molecular Weight	222.99 g/mol
Synonyms	6-Iodo-2-fluoropyridine; 2-Fluoro-6-iodopyridine; Pyridine, 2-fluoro-6-iodo-; 2-Fluoropyridine-6-iodide; 6-Iodo-2-fluoro-pyridine; FIP; 2-F-6-I-Pyridine
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-Iodopyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting purity, assay, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.