Description

3-Chloro-2-Fluoro-5-Phenylpyridine is a high-value, multi-functional heterocyclic building block of significant importance in modern synthetic chemistry. Its unique halogenated pyridine core with a phenyl substituent makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Serves as a versatile precursor for creating advanced herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Used in the development of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Ligand and Catalyst Development: The nitrogen and halogen atoms provide coordination sites for creating novel ligands used in transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: An essential building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Chloro-2-Fluoro-5-Phenylpyridine
CAS No.	1214341-47-5
Molecular Formula	C11H7ClFN
Molecular Weight	207.63 g/mol
Synonyms	3-Chloro-2-fluoro-5-phenylpyridine; 5-Phenyl-3-chloro-2-fluoropyridine; 2-Fluoro-3-chloro-5-phenylpyridine; Pyridine, 3-chloro-2-fluoro-5-phenyl-; 1214341-47-5; 3-Chloro-2-fluoro-5-phenyl-pyridine
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Fluoro-5-Phenylpyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.